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Lipodissolve Los Angeles

Lipodissolve is a fat dissolving product very similar to Kybella. When injected into localized fat deposits of the body, Lipodissolves dissolves the fat and tones the area. Lipodissolve has been used in Brazil and Europe for more than 40 years, and in the United States for more than twenty years.




Phosphatidylcholine and Sodium Deoxycholate, two substances that naturally occur in the body, are the primary active components in Lipodissolve, often with mixed in numbing medication, like Lidocain. Other substances like pentoxifylline, aminophylline, calcitonin, isoproterenol, caffeine, vitamins, minerals, or herbal extracts are sometimes added to the mix, but are of questionable value and are not proven to add to the effectiveness of the treatment. The Lipodissolve that is used by Dr. R. Dishakjian, the cosmetic surgeon at our medical spa, is prepared by a reputable, state-licensed U.S. compounding pharmacy, and is as effective as Kybella.

The combination of Phosphatidylcholine/Sodium Deoxycholate works by disrupting the fat cells and emulsifying the contents. The emulsion is then flushed from the body as waste. The inflammatory response in the process causes new collagen to form beneath the skin. As a result, the skin often becomes firmer and denser. Clinical studies have indicated that sodium deoxycholate, an anionic bile detergent, is the major active substance that causes emulsification and subsequent lipolysis.

Lipodissolve and FDA Approval

Lipodissolve has not been approved or intensely tested by the FDA for fat reduction or cosmetic purposes. The application of Lipodissolve for cosmetic fat reduction is considered “off-label” use. Off-label use of a medication; however, does not mean that its use is illegal; unless clearly specified or banned by the FDA. Most people are surprised to learn that the FDA does not test drugs. Instead, the manufacturer must prove to the FDA that the product is safe and effective. This, of course, is a very costly process, running in the hundreds of millions of dollars. For substances like Lipodissolve, that are commonly used and already in the public domain, and therefore not eligible, like Kybell, for exclusive patents, pharmaceutical companies will not incur the expense of FDA testing without the prospect of recouping their investments through the exclusive right to the sales of the product at a profitable sales price. Interestingly, in the area of dermatology, about one-third of all prescriptions written are not approved by the FDA.


Safety of Lipodissolve

For more than 40 years, the fat dissolving  procedure with Lipodissolve injections has been performed on millions of patients. Lipodissolve is normally safe, as long as patients are carefully selected and the physician is adequately trained. Dr. R. Dishakjian, the cosmetic surgeon at Nu Vela, has safely performed thousands of lipotherapy, body contouring and scupting treatments, without coming across even one case of serious side effects, apart from the known common side effects. Dr. Dishakjian is a member of the International Meso-Lipotherapy Society and has received accredited lipotherapy training. Dr. Dishakjian has been featured on abc channel’s Eyewitness News in order to express his expert opinion on the effectiveness and safety of Lipodissolve injections when used for body contouring purposes.

Phosphatidylcholine and Deoxycholate are both naturally found in the human body. In fact, Phosphatidylcholine is a vital substance that is present in every cell in the human body. When we are born, it is found in very high concentrations in the brain tissue. However, these levels decline over time as a normal part of aging process. Phosphatidylcholine is also contained in eggs, soybeans, mustard, sunflower, and other foods.

Besides its use in lipotherapy, Phosphatidylcholine has many applications in medicine; for example, healthcare providers sometimes give phosphatidylcholine intravenously (by IV) for chest pain, fat globules in the blood (fat embolism), high cholesterol, liver disease, and fatty plaque deposits in arteries. Because the body uses phosphatidylcholine to make a brain chemical called acetylcholine, there is some interest in using it for treating brain-related conditions such as memory loss, Alzheimer’s disease, anxiety, manic-depressive disorders, and a movement disorder called tardive dyskinesia. Many studies have found Phosphatidylcholine supplements can improve learning, aid memory, help promote healthy skin elasticity, and even support optimal liver function.

Sodium deoxycholate is the sodium salt of deoxycholic acid. The latter is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. In the human body deoxycholic acid is used in the emulsification of fats for the absorption in the intestine. It has, in some countries (including Switzerland) been licensed as an emulsifier in food industry, but it is no longer common. It is also sometimes used to prevent and dissolve gallstones.

Fat Reduction and Body Contouring with Lipodissolve

Lipodissolve can be used for body contouring to reduce localized fat deposits virtually from any part of the human body. In addition, it is very effective to correct plumped jowls and to get rid of fat in the under chin area. The technique is commonly known as lipotherapy.

Please go to lipotherapy to read about the application of lipotherapy in body contouring, or call 818-832-4500 to schedule a consultation with Dr.Dishakjian. During your initial consultation, Dr. Dishakjian will examine the target areas and discuss your best options and answer any questions you may have about the actual procedure. He will also give you an estimate of the number of treatment sessions needed to achieve the desired results.